When it’s the nervous system and muscles that are causing facial expressions to cause wrinkles and frown lines, Botulinums are the easy solution and answer to correct this. Botulinums, with the most popular known as Botox, act to inhibit chemicals inside the nervous system which normally cause muscle contraction and frowning. Without the chemical signal, muscles are relaxed and the face is frown and wrinkle free and expressions are normal. Botulinums are also used to treat neck or head pain and treat eye muscle spasms.